TSSP1 - DrugMatrix
DrugMatrix, produced by the U.S. National Toxicology Program, is a molecular toxicology reference database and informatics system. DrugMatrix is populated with the comprehensive results of thousands of highly controlled and standardized toxicological experiments in which rats or primary rat hepatocytes were systematically treated with therapeutic, industrial, ... [more] TOXsIgN May 11, 2020, 12:24 p.m.

TSSP2 - Open TG-GATEs
Open TG-GATEs is a toxicogenomics database open to the public for researchers to utilize research results of TGP and TGP2, and releases the data of 170 compounds stored in TG-GATEs. In Open TG-GATEs, it is possible to search toxicogenomics data by compound name or pathological finding. It is also possible ... [more] TOXsIgN May 11, 2020, 12:24 p.m.

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TSP736 - Triazole Antifungal Toxicogenomics: GeneLogic_Triazoles
Public

The modes of triazole reproductive toxicity have been characterized by an observed increased in serum testosterone and reduced insemination and fertility indices. The key events involved in the disruption in ...

[more]
TOXsIgN Jan. 28, 2020, 9:53 a.m.

TSP737 - Triazole Antifungal Toxicogenomics: Iconix3_Triazoles
Public

The modes of triazole reproductive toxicity have been characterized by an observed increased in serum testosterone and reduced insemination and fertility indices. The key events involved in the disruption in ...

[more]
TOXsIgN Jan. 28, 2020, 9:53 a.m.

TSP738 - Triazole Antifungal Toxicogenomics: rat_repro_Liver
Public

The modes of triazole reproductive toxicity have been characterized by an observed increased in serum testosterone and reduced insemination and fertility indices. The key events involved in the disruption in ...

[more]
TOXsIgN Jan. 28, 2020, 9:53 a.m.

TSP739 - Triazole Antifungal Toxicogenomics: rat_repro_Testis
Public

The modes of triazole reproductive toxicity have been characterized by an observed increased in serum testosterone and reduced insemination and fertility indices. The key events involved in the disruption in ...

[more]
TOXsIgN Jan. 28, 2020, 9:53 a.m.

TSP740 - Genetical toxicogenomics of lead treatment
Public

75 Diosophilia Roo lines, recominant inbred lines, were raised to adulthood either on conventional diet or diet supplemented with lead acetate. Whole flies were used for RNA extraction. RNA was ...

[more]
TOXsIgN Jan. 28, 2020, 9:53 a.m.

TSA1 - DrugMatrix - Toxicogenomic signatures of Liver after exposure to nitrazepam (310 mg/kg, 3 days) in the rat
Organism Tissue Cell Cell line Sex Stage
Public / / Male Adulthood
TSA2 - DrugMatrix - Toxicogenomic signatures of Kidney after exposure to 4-nonylphenol (200 mg/kg, 5 days) in the rat
Organism Tissue Cell Cell line Sex Stage
Public / / Male Adulthood
TSA3 - DrugMatrix - Toxicogenomic signatures of Kidney after exposure to 4-nonylphenol (200 mg/kg, 1 days) in the rat
Organism Tissue Cell Cell line Sex Stage
Public / / Male Adulthood
TSA4 - DrugMatrix - Toxicogenomic signatures of Heart after exposure to oxybutynin (230 mg/kg, 5 days) in the rat
Organism Tissue Cell Cell line Sex Stage
Public / / Male Adulthood
TSA5 - DrugMatrix - Toxicogenomic signatures of Heart after exposure to oxybutynin (230 mg/kg, 3 days) in the rat
Organism Tissue Cell Cell line Sex Stage
Public / / Male Adulthood
TSS1 - DrugMatrix - Toxicogenomic signatures of Liver after exposure to nitrazepam (310 mg/kg, 3 days) in the rat
Organism Tissue Cell Cell line Chemical Sex Stage Up genes Down genes
Public Genomics / / Nitrazepam Male Adulthood 4 20

TSS2 - DrugMatrix - Toxicogenomic signatures of Kidney after exposure to 4-nonylphenol (200 mg/kg, 5 days) in the rat
Organism Tissue Cell Cell line Chemical Sex Stage Up genes Down genes
Public Genomics / / 4-nonylphenol Male Adulthood 9 2

TSS3 - DrugMatrix - Toxicogenomic signatures of Kidney after exposure to 4-nonylphenol (200 mg/kg, 1 days) in the rat
Organism Tissue Cell Cell line Chemical Sex Stage Up genes Down genes
Public Genomics / / 4-nonylphenol Male Adulthood 0 0

TSS4 - DrugMatrix - Toxicogenomic signatures of Heart after exposure to oxybutynin (230 mg/kg, 5 days) in the rat
Organism Tissue Cell Cell line Chemical Sex Stage Up genes Down genes
Public Genomics / / Oxybutynin Male Adulthood 33 33

TSS5 - DrugMatrix - Toxicogenomic signatures of Heart after exposure to oxybutynin (230 mg/kg, 3 days) in the rat
Organism Tissue Cell Cell line Chemical Sex Stage Up genes Down genes
Public Genomics / / Oxybutynin Male Adulthood 0 0