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TSS8507 - Ctrl_Male Vs Exposed_Male PublicInterventional
No up/down regulated genes
Genomic signature information
Data analysis was performed using and the AMEN suite of tools (Chalmel & Primig, 2008). Briefly, genes showing a signal higher than a given background cutoff (median of the normalized dataset) and at least a 1.5-fold change in at least one pairwise comparison were selected. To define a set of 364 genes displaying significant statistical changes across comparisons, the empirical Bayes moderated t-statistics was performed using the limma package (F-value adjusted using the Benjamini & Hochberg (BH) False Discovery Rate approach, p =< 0.05) . The resulting genes were then partitioned into two broad expression clusters (termed C1 and C2) using the k-means algorithm.